Isotopically Labeled Compounds
Medchemexpress LLC Tiopronin-13c,d3 | 1189695-13-3 | ≥98% | 1 MG
Tiopronin-13C,d3 is a deuterium labeled form of Tiopronin. Tiopronin is known as a diffusible antioxidant, an antidote for heavy metal poisoning, and a radioprotective agent. This compound can help control the rate of cystine precipitation and excretion, showing potential for use in treating conditions like cystinuria, rheumatoid arthritis, and various hepatic disorders.
- Deuterium labeled Tiopronin
- Functions as a diffusible antioxidant
- Acts as an antidote to heavy metal poisoning
- Serves as a radioprotective agent
- Shows potential for cystinuria, rheumatoid arthritis, and hepatic disorders
Medchemexpress LLC D-Glucose-d2 | 18991-62-3 | MFCD00064367 | 99.9% | 50 MG
D-Glucose-d2 is a deuterium-labeled form of D-Glucose. D-Glucose, a monosaccharide, plays a vital role in biology as an important carbohydrate. It acts as a carbohydrate sweetener, a critical component of general metabolism, and a signaling molecule related to cellular metabolic status and biotic and abiotic stress responses.
- Can be utilized as a tracer.
- Can serve as an internal standard for quantitative analysis using methods such as NMR, GC-MS, or LC-MS.
- Stable heavy isotopes, like deuterium, are incorporated into drug molecules for quantitation during drug development processes.
- Deuteration can potentially influence the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Dopamine-d3 (hydrochloride) | 53587-30-7 | 99.9% | 5 MG
Dopamine-d3 (hydrochloride) is the deuterium labeled Dopamine hydrochloride (ASL279)-. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Pentoxifylline-d5 | 1185995-18-9 | 99.9% | 50 MG
Pentoxifylline-d5 is a deuterium-labeled version of Pentoxifylline. The unlabeled compound, Pentoxifylline (BL-191), acts as a haemorheological agent and is an orally active, non-selective phosphodiesterase (PDE) inhibitor. It demonstrates immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic, and anti-proliferation effects. This compound can be utilized in research concerning peripheral vascular disease, cerebrovascular disease, and other conditions involving impaired regional microcirculation.
- Used as a tracer.
- Functions as an internal standard for quantitative analysis through methods like NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development.
- Deuteration can influence the pharmacokinetic and metabolic profiles of compounds.
Medchemexpress LLC Glipizide-d11 | 1189426-07-0 | 96.4% | 5 MG
Glipizide-d11 is the deuterium labeled Glipizide. Glipizide (CP 2872; K 4024) is a potent, orally active, sulfonylurea class anti-diabetic agent used for type 2 diabetes mellitus research, but not for type 1. Glipizide acts by partially blocking ATP-sensitive potassium (KATP) channels among β cells of pancreatic islets of Langerhans.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can impact the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Phenindione-d5 | 70711-53-4 | 99.5% | 1 MG
Phenindione-d5 is deuterium labeled Phenindione, an anticoagulant that functions as a Vitamin K antagonist. It is for research use only and not sold to patients.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC L-Isoleucine-¹⁵N,d10 | 73-32-5 | 142.23 | 5 MG
L-Isoleucine-15N,d10 is an isotopically labeled form of L-Isoleucine, an essential amino acid. This compound is enriched with both deuterium (d10) and nitrogen-15 (15N) isotopes, making it highly valuable for various research applications. It is commonly employed in studies involving protein structure and dynamics, metabolic pathways, and nuclear magnetic resonance (NMR) spectroscopy, where isotopic labeling helps in tracing and identifying specific molecules and their interactions.
- Isotopically labeled for research applications.
- Enriched with deuterium and nitrogen-15 isotopes.
- Useful for tracing metabolic pathways.
- Ideal for NMR spectroscopy studies.
- Supports research in protein structure and dynamics.
Medchemexpress LLC Diphenhydramine-d5 hydrochloride | 1219795-16-0 | 99.8% | 1 MG
Diphenhydramine-d5 hydrochloride is a deuterium-labeled form of Diphenhydramine hydrochloride. This compound acts as a first-generation histamine H1-receptor antagonist with anticholinergic effects and can cross the ovine blood-brain barrier (BBB). It is intended for research use only.
- Can be used as a tracer
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs
- Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development
Medchemexpress LLC o-cresol-d7 | 202325-50-6 | MFCD03428136 | 95.0% | 115.18 | C7HD7O | 25 MG
o-Cresol-d7 is the deuterium-labeled form of o-cresol supplied as a stable isotope standard for use in mass spectrometry and metabolite studies. It serves as an internal standard and tracer for quantitative analyses of cresol metabolites and related biochemical pathways.
- Deuterium-labeled internal standard for mass spectrometry.
- Suitable for quantitative analysis of cresol metabolites.
- Available in small milligram pack sizes for trace-level work.
- Includes product datasheet and handling instructions for laboratory use.
Medchemexpress LLC Azithromycin-d5 | 83905-01-5 | 754.02 | C38H67D5N2O12 | 1 MG
Azithromycin-d5 is the deuterium-labeled analogue of azithromycin, a macrolide antibiotic. It is supplied for research use as an internal standard and tracer in quantitative analytical workflows, supporting pharmacokinetic and metabolic studies where isotopically labeled standards improve accuracy and precision.
- Deuterium-labeled internal standard for quantitative analysis.
- Suitable for LC-MS, GC-MS, and NMR applications.
- Offered in small-scale analytical packaging (e.g., 1 mg).
- Molecular formula C38H67D5N2O12; molecular weight 754.02.
- Certificate of analysis/data sheet available for analytical use.
Medchemexpress LLC Leucovorin-d4 (calcium hydrate) | >90.0% | 533.54 | C20H19D4CaN7O8 | 250 UG
Leucovorin-d4 (calcium hydrate) is a deuterium-labeled folinic acid supplied as the calcium hydrate salt for research and analytical applications. It is provided as a small research-grade standard (250 μg) with a listed purity of >90% and is not intended for human use.
- Deuterium-labeled folinic acid for use as an isotope standard.
- Calcium hydrate form suitable for analytical workflows.
- Purity >90.0% as specified by the supplier.
- Molecular formula C20H19D4CaN7O8 and molecular weight 533.54.
- Supplied in a 250 μg research pack for analytical or mass spectrometry applications.
- Not intended for human or clinical use; for research use only.
Medchemexpress LLC Piperacillin-d5 | 61477-96-1 | 96.0% | 522.59 | C23H22D5N5O7S | 10 MG
Piperacillin-d5 is a deuterium-labeled (d5) analogue of the β-lactam antibiotic piperacillin supplied as a solid powder for use as an internal standard and tracer in quantitative analyses by NMR, GC-MS, and LC-MS. The d5 labeling enables mass-based discrimination with minimal alteration of chemical properties, making it suitable for pharmacokinetic and bioanalytical studies.
- Deuterium-labeled (d5) internal standard for quantitative analysis.
- Solid powder form for analytical sample preparation.
- Purity approximately 96.0%.
- Molecular weight 522.59 g/mol; formula C23H22D5N5O7S.
- Offered in small pack sizes for analytical workflows (for example, 10 mg).
Medchemexpress LLC Thiabendazole-d4 | 1190007-20-5 | 98.8% | 205.27 g/mol | C10H3D4N3S | 10 MG
Thiabendazole-d4 is the deuterated isotopologue of thiabendazole, supplied as a solid stable isotope-labeled reference material for analytical and research use. It is formulated for use as an internal standard and reference in mass spectrometry and quantitative assays.
- Deuterated internal standard for mass spectrometry and quantitative assays.
- High chemical purity (98.84%) for reliable analytical performance.
- White to off-white solid, suitable for handling and weighing.
- Available in small, accurately weighed sizes for reference and calibration.
- Powder stable at -20°C for long-term storage; solvent stability is limited and should follow recommended conditions.
Medchemexpress LLC Ketotifen-d3 fumarate | 1795138-23-6 | 99.2% | 50 MG
Ketotifen-d3 (fumarate) is a deuterium-labeled version of Ketotifen fumarate. This compound is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer, utilized for the prevention of asthma attacks.
- Can be used as a tracer.
- Can serve as an internal standard for quantitative analysis through methods like NMR, GC-MS, or LC-MS.
Medchemexpress LLC Ketoprofen-13C,d3 | 1189508-77-7 | 1 MG
Ketoprofen-13C,d3 is the 13C- and deuterium labeled Ketoprofen. Ketoprofen is a non-steroidal antiinflammatory agent, acting as a potent inhibitor of COX, with IC50s of 2 nM and 26 nM for COX-1 and COX-2 in human blood monocytes, respectively.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes of hydrogen, carbon, and other elements for quantitation during drug development.
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs.