Isotopically Labeled Compounds
Cayman Chemical DL-AspartIcAcId-d3 25mg
An internal standard for the quantification of aspartic acid by GC- or LC-MS
Cayman Chemical IloperIdon-d3 25mg
An internal standard for the quantification of iloperidone by GC- or LC-MS
Cayman Chemical CystathIonIn-d4 1mg
An internal standard for the quantification of cystathionine by GC- or LC-MS
Medchemexpress LLC Amantadine-d6 | 1219805-53-4 | 98.1% | 5 MG
Amantadine-d6 is the deuterium labeled Amantadine. Amantadine (1-Adamantanamine) is an orally active and potent antiviral agent effective against influenza A viruses. It inhibits various ion channels, including NMDA and M2, as well as Coronavirus ion channels. It also exhibits anti-orthopoxvirus and anticancer activities. Amantadine-d6 can serve as a tracer and an internal standard for quantitative analysis, with deuteration potentially influencing pharmacokinetic and metabolic profiles of drugs. Applications include research for Parkinson's disease, postoperative cognitive dysfunction (POCD), and COVID-19.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes incorporated into drug molecules for quantitation
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Adenosine-d13 | 58-61-7 | 96.6% | 1 MG
Adenosine-d13 is a deuterium-labeled version of Adenosine, a widely present endogenous autacoid. It functions by activating four G protein-coupled receptors (A1, A2A, A2B, and A3), influencing various cellular physiological processes including neuronal activity, vascular function, platelet aggregation, and blood cell regulation. This compound is intended for research use only.
- Can be used as a tracer or internal standard for quantitative analysis.
- Suitable for techniques like NMR, GC-MS, or LC-MS.
- Incorporation of stable heavy isotopes, such as deuterium, into drug molecules may impact pharmacokinetic and metabolic profiles.
Medchemexpress LLC Lidocaine-d10 | 851528-09-1 | 98.9% | 5 MG
Lidocaine-d10 | 851528-09-1 | 98.9% | 5 MG
Medchemexpress LLC L-Hydroxyproline-d3 | 1356016-86-8 | 99.9% | 134.15 | 1 MG
L-Hydroxyproline-d3 is the deuterium labeled L-Hydroxyproline. L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 2 2-Bipyridine-d8 | MFCD00190432 | 99.3% | 164.24 g/mol | C10D8N2 | 25 MG
2,2'-Bipyridine-d8 is the deuterium-labeled isotopologue of 2,2'-bipyridine supplied as a white to off-white solid. It is used as an isotopically labeled reagent or internal standard in organic synthesis, mechanistic studies, and mass spectrometry.
- High isotopic enrichment suitable for analytical standards.
- High purity (99.3%) for reliable research results.
- Solid form enables accurate weighing and convenient storage.
- Suitable as a ligand in coordination chemistry and mechanistic investigations.
- Available in small, research-scale pack sizes for lab use.
Medchemexpress LLC Allopurinol | 315-30-0 | 100.0% | 1 ML
Allopurinol is a potent and orally active xanthine oxidase inhibitor with an IC50 value of 0.2-50 μM. It can be used in the research of hyperuricemia and gout. It decreases the expression of HIF-1α and HIF-2α protein. It also shows anti-depressant and anti-nociception activity, and anti-leishmanial effect.
- Potent and orally active xanthine oxidase inhibitor
- Can be used in the research of hyperuricemia and gout
- Decreases the expression of HIF-1α and HIF-2α protein
- Reduces angiogenesis traits of HUVEC cells
- Exhibits anti-depressant activity in mouse models
- Induces anti-nociception activity in mouse models
- Shows anti-leishmanial effect
Medchemexpress LLC Fenofibric acid-d6 | 1092484-69-9 | 99.6% | 5 MG
Fenofibric acid-d6 (FNF acid-d6) is the deuterium-labeled form of Fenofibric acid. Fenofibric acid, an active metabolite of fenofibrate, acts as a PPAR activator with EC50s of 22.4 μM for PPARα, 1.47 μM for PPARγ, and 1.06 μM for PPARδ. It also inhibits COX-2 enzyme activity with an IC50 of 48 nM. Deuterium substitution in drug molecules is of interest due to its potential impact on pharmacokinetic and metabolic profiles.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- For research use only.
Medchemexpress LLC Phenacetin-d5 | 69323-74-6 | 99.5% | 1 ML
Phenacetin-d5 is the deuterium labeled version of Phenacetin. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent, a selective COX-3 inhibitor, and is used as a probe for cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC D-Glucose-13C-3 | 105931-74-6 | 99.7% | 250 MG
D-Glucose-13C-3 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and a critical component of general metabolism, serving as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Amlodipine-d4 maleate | 2714486-25-4 | 98.2% | 1 MG
Amlodipine-d4 maleate | 2714486-25-4 | 98.2% | 1 MG
Medchemexpress LLC 2,2'-bipyridine-d8 | 32190-42-4 | 99.3% | 164.23 g·mol⁻1 | C10D8N2 | 200 MG
2,2'-Bipyridine-d8 is the deuterium-labeled analogue of 2,2'-bipyridine supplied as a high-purity solid for use as a stable-isotope reagent and analytical standard. It is intended for mechanistic studies, tracer experiments, and as an internal standard in mass-spectrometry workflows where deuterium labeling improves tracking and quantification.
- High isotopic purity for accurate mass-spectrometry analysis.
- Suitable as an internal standard and tracer in analytical workflows.
- Solid form convenient for storage and handling.
- Commonly used in coordination chemistry and ligand studies.
- Supplied in a 200 mg pack size suitable for small-scale experiments.
Medchemexpress LLC C18 glucosyl(β) ceramide (d18:1/18:0) | 95119-86-1 | 99.9% | 728.09 g/mol | C42H81NO8 | 10 MG
GlcCer (d18:1/18:0) is a C18 glucosylceramide glycosphingolipid used as a biochemical research reagent for studies of glycosphingolipid metabolism and neurodegenerative disorders, including Parkinson disease and dementia with Lewy bodies. The compound is supplied as a solid for dissolution in organic solvent and is characterized by formula C42H81NO8 and molecular weight 728.09 g/mol.
- Used in studies of glycosphingolipid biology and neurodegeneration.
- Suitable for biochemical and cellular assays.
- Soluble in DMSO; ultrasonic treatment may be required for full dissolution.
- Stable as powder at -20°C for extended storage.
- High purity appropriate for research applications.